23andMe DNA test that is.
Guess what? I am 100% me.
I am the same me, made up of the same cells that I was before these reports as I am afterward.
23andMe website states ” Learn over 70 things about yourself” which I’m pretty sure is a stretch but hey we seldom spend money on things we don’t need and it was interesting if nothing else, plus we can count it as an early birthday present for me.
I’ve heard the ancestry part is a lot on how your sample is read or interpreted. There was a case of identical triplets that had varying degrees of heritage. I also know that I have more Indian / Native American than .3% and my husband has more than 0.0%. It says we both have “likely lighter skin” and we’re both olive to darker complexion.
We all have some Neaderthal they say… but scientist also say we go back billions of years. I’m sticking to the made in God’s image descended from Adam & Eve. The report says Neanderthalsis reflected in our height. Best I can see they mean tall – which me, my mom and dad were all shorter than average. It also says I have more Neanderthal variants than 61% of their customers.
When I did the free trial at ancestry.com, I went back to the 1600-1700 and found German on both sides of my tree. I had to go back a loonnngg way to even get my husbands out of the Carolinas. When he says native [Carolina] – he means it! Oddly enough hubby and I both have “3 close family to second cousins” in their database and about the same amount of 3rd to 4th and 5th to distant.
I think the health / medical aspect offered by, I think, only 23andme would be valuable to those considering a family, but this was the most important part for me, especially after sending the data they extracted to Promethease.
Most of the traits could be found (more accurately) but looking into a mirror. For instance- my hair is pretty darn curly to say “likely straight to wavy,” and since my mom and uncle had red hair and that’s the color mine tends to go if I lighten it, I’d say there’s more than 0% chance I’ve got red hair in my genes.
This original report didn’t say anything about me losing my sense of smell and diminished ability to taste. It did say I likely did not have a hereditary hearing loss. It’s a fact that I’m more sensitive to sound than most, have had tinnitus ringing in my ear for years now, and that my mom and grandma both are/were hearing impaired. It also didn’t mention the 3 of us also had thyroid problems. The 23andme test alone, didn’t address that I have migraines (that run in my family and wiped out a good portion of last week) or that I’ve become lactose intolerant as I’ve aged. They didn’t say my hubby has celiac.
I knew it was off when they said I was not likely to have a cat.
Oh and this one will make you laugh if you know me … are you ready? They said I have muscle composition common in elite power athletes. That’d be a big WRONG. I have nothing in common with elite power athletes. They said the same about my hubby who played and did well in all sorts of sports.
They said we are both less likely to be deep sleepers, although I have likely average to less sleep movement and hubby has likely more than average. Hubby has always slept horribly, and you could about tear down our house and I wouldn’t wake up. Hubby does joke though that he can get up or be coughing during the night and I don’t even budge but let one of the cats make a funny sound and I’m up and checking on them. Let’s attribute that to the fact that if he needs me awake I know he can wake me. It did say I’m likely to weigh more than average so at least there is some DNA to back up that all to real struggle.
They also said I had less empathy under stress. I actually don’t know anyone else who tears up more for others, things I see or feel than me. Ask anyone who knows me. Maybe I have less under stress but the only time I can think of that I know that to be true is on fear when my body chooses flight over fight without even considering what the other people around me are doing.
I dug a little deeper for an extra $5 bucks each to send our samples to Promethease. With 23andme you can download your raw data so you’ve just got the DNA facts without someone’s interpretation and upload it to Promethease for a much more detailed report. I’m not sure yet if that includes the separate ancestry csv file or not.
Now that is an in-depth report!
It shows things like your reaction to medications and all sorts of health info. It did say I was likely to have migraines. It did know I get ridiculously sick with anesthesia. It said hubby was more likely to have celiac disease. If you share your data, which I didn’t do you can compare data I think if you upload the files at the same time. Probably another $5. Now Promethease doesn’t actually extract the data. They show you all your genetic markers in something that would probably take thousands of pages to print. They don’t store it either but they do let you download it. This addition made me feel like I had a much more complete report.
I’m still not sure how they gauge your risk factors. Do they take people with similar DNA and say that if you have that same variant chromosome you are more or less at risk than someone without a certain variant to that gene?
For example, they reported I am more at risk for prostate cancer and my hubby is more at risk for ovarian cancer. Pretty sure we’d have a lot more issues than that if we had those bits.
Amusing and interesting, but I plan to keep walking, hiking, enjoying this beautiful thing called life, taking omega, curcumin, and plenty of pictures, loving Jesus, my family, my friends and my cats and every now and then brownies.
This what the ancestry with health test report on, but there is a whole lotta ‘not tested’ too.
Alpha-1 Antitrypsin Deficiency
2 variants in the SERPINA1 gene; relevant for European descent
2 variants in the F5 and F2 genes; relevant for European descent
Late-Onset Alzheimer’s Disease
1 variant in the APOE gene; variant found and studied in many ethnicities
2 variants in the LRRK2 and GBA genes; relevant for European, Ashkenazi Jewish, North African Berber descent
- Alcohol Flush Reaction
- Caffeine Consumption
- Deep Sleep
- Genetic Weight
- Lactose Intolerance
- Muscle Composition
- Saturated Fat and Weight
- Sleep Movement
- Asparagus Odor Detection
- Back Hair (available for men only)
- Bald Spot (available for men only)
- Bitter Taste Perception
- Cheek Dimples
- Cleft Chin
- Earlobe Type
- Earwax Type
- Eye Color
- Finger Length Ratio
- Hair Curliness
- Light or Dark Hair
- Male Hair Loss (available for men only)
- Newborn Hair Amount
- Photic Sneeze Reflex
- Red Hair
- Skin Pigmentation
- Sweet Taste Preference
- Toe Length Ratio
- Widow’s Peak
1 variant in the SACS gene; relevant for French Canadian descent
Agenesis of the Corpus Callosum with Peripheral Neuropathy
1 variant in the SLC12A6 gene; relevant for French Canadian descent
Autosomal Recessive Polycystic Kidney Disease
3 variants in the PKHD1 gene
Beta Thalassemia and Related Hemoglobinopathies
10 variants in the HBB gene; relevant for Cypriot, Greek, Italian, Sardinian descent
1 variant in the BLM gene; relevant for Ashkenazi Jewish descent
3 variants in the ASPA gene; relevant for Ashkenazi Jewish descent
Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)
2 variants in the PMM2 gene; relevant for Danish descent
28 variants in the CFTR gene; relevant for European, Hispanic/Latino, Ashkenazi Jewish descent
D-Bifunctional Protein Deficiency
2 variants in the HSD17B4 gene
Dihydrolipoamide Dehydrogenase Deficiency
1 variant in the DLD gene; relevant for Ashkenazi Jewish descent
1 variant in the IKBKAP gene; relevant for Ashkenazi Jewish descent
Fanconi Anemia Group C
3 variants in the FANCC gene; relevant for Ashkenazi Jewish descent
1 variant in the BCS1L gene; relevant for Finnish descent
Gaucher Disease Type 1
3 variants in the GBA gene; relevant for Ashkenazi Jewish descent
Glycogen Storage Disease Type Ia
1 variant in the G6PC gene; relevant for Ashkenazi Jewish descent
Glycogen Storage Disease Type Ib
2 variants in the SLC37A4 gene
Hereditary Fructose Intolerance
3 variants in the ALDOB gene; relevant for European descent
Herlitz Junctional Epidermolysis Bullosa (LAMB3-related)
3 variants in the LAMB3 gene
Leigh Syndrome, French Canadian Type
1 variant in the LRPPRC gene; relevant for French Canadian descent
Limb-Girdle Muscular Dystrophy Type 2D
1 variant in the SGCA gene; relevant for Finnish descent
Limb-Girdle Muscular Dystrophy Type 2E
1 variant in the SGCB gene; relevant for Southern Indiana Amish descent
Limb-Girdle Muscular Dystrophy Type 2I
1 variant in the FKRP gene; relevant for European descent
3 variants in the ACADM gene; relevant for Northern European descent
Maple Syrup Urine Disease Type 1B
2 variants in the BCKDHB gene; relevant for Ashkenazi Jewish descent
Mucolipidosis Type IV
1 variant in the MCOLN1 gene; relevant for Ashkenazi Jewish descent
Neuronal Ceroid Lipofuscinosis (CLN5-Related)
1 variant in the CLN5 gene; relevant for Finnish descent
Neuronal Ceroid Lipofuscinosis (PPT1-Related)
3 variants in the PPT1 gene; relevant for Finnish descent
Niemann-Pick Disease Type A
3 variants in the SMPD1 gene; relevant for Ashkenazi Jewish descent
Nijmegen Breakage Syndrome
1 variant in the NBN gene; relevant for Eastern European descent
Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related)
2 variants in the GJB2 gene; relevant for Ashkenazi Jewish, European descent
Pendred Syndrome and DFNB4 Hearing Loss
6 variants in the SLC26A4 gene
Phenylketonuria and Related Disorders
23 variants in the PAH gene; relevant for Northern European descent
Primary Hyperoxaluria Type 2
1 variant in the GRHPR gene; relevant for European descent
Rhizomelic Chondrodysplasia Punctata Type 1
1 variant in the PEX7 gene
1 variant in the SLC17A5 gene; relevant for Finnish, Swedish descent
Sickle Cell Anemia
1 variant in the HBB gene; relevant for African descent
1 variant in the ALDH3A2 gene; relevant for Swedish descent
4 variants in the HEXA gene; relevant for Ashkenazi Jewish, Cajun descent
Tyrosinemia Type I
4 variants in the FAH gene; relevant for French Canadian, Finnish descent
Usher Syndrome Type 1F
1 variant in the PCDH15 gene; relevant for Ashkenazi Jewish descent
Usher Syndrome Type 3A
1 variant in the CLRN1 gene; relevant for Ashkenazi Jewish descent
Zellweger Syndrome Spectrum (PEX1-Related)
1 variant in the PEX1 gene